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Table 1 Characteristics of the study populations

From: Explainable machine learning algorithm to predict cardiovascular event in patients undergoing peritoneal dialysis

Variables

Total (n = 318)

No CVE group (n = 208)

CVE group (n = 110)

P Value

Male n (%)

152 (47.8)

98 (47.1)

54 (49.1)

0.83

Age (years)

52.00 (41.25, 61.00)

50.00 (39.00, 60.00)

56.00 (47.00, 63.00)

 < 0.01

Body mass index (kg/m2)

21.74 (19.73, 23.95)

21.76 (19.70, 23.88)

21.66 (19.80, 24.37)

0.86

Diabetes mellitus n (%)

65 (20.4)

37 (17.8)

28 (25.5)

0.14

Cardiovascular disease n (%)

44 (13.8)

24 (11.5)

20 (18.2)

0.14

Fibrinogen (g/L)

3.58 (2.89, 4.48)

3.42 (2.88, 4.26)

3.71 (2.89, 4.67)

0.06

Hemoglobin (g/L)

76.00 (63.00, 90.00)

75.00 (62.75, 88.00)

77.50 (63.00, 90.75)

0.87

White blood count (109/L)

5.46 (4.48, 7.08)

5.37 (4.40, 6.91)

5.70 (4.67, 7.29)

0.16

Platelet count (109/L)

140.50 (104.00, 180.75)

132.00 (99.75, 179.25)

149.50 (116.25, 182.50)

0.02

Serum creatinine (μmol/L)

810.00 (665.25, 1010.00)

830.00 (692.25, 1041.25)

768.00 (625.50, 982.25)

0.06

Serum urea nitrogen (mmol/L)

29.93 (22.70, 39.48)

31.28 (23.77, 40.60)

26.66 (20.23, 38.28)

0.01

Serum uric acid (μmol/L)

490.00 (413.50, 591.00)

490.50 (424.00, 591.50)

490.00 (405.25, 570.25)

0.50

Serum corrected calcium (mmol/L)

2.08 (1.84, 2.23)

2.08 (1.81, 2.23)

2.09 (1.92, 2.24)

0.33

Serum phosphorus (mmol/L)

1.90 (1.56, 2.31)

1.94 (1.59, 2.33)

1.85 (1.53, 2.27)

0.54

Serum albumin (g/L)

33.22 ± 5.69

33.88 ± 5.54

31.97 ± 5.79

 < 0.01

Alkaline phosphatase (U/L)

82.00 (64.00, 106.00)

83.00 (64.00, 105.50)

79.50 (64.00, 106.00)

0.88

Total cholesterol (mmol/L)

3.95 (3.31, 4.76)

3.84 (3.22, 4.67)

4.04 (3.40, 4.95)

0.07

Triglyceride (mmol/L)

1.15 (0.84, 1.59)

1.18 (0.83, 1.60)

1.09 (0.86, 1.55)

0.61

Fasting blood glucose (mmol/L)

4.78 (4.35, 5.38)

4.72 (4.35, 5.28)

4.87 (4.37, 5.49)

0.25

Ferritin (μg/L)

195.00 (81.60, 321.25)

183.50 (75.70, 333.50)

201.50 (86.52, 305.75)

0.87

Transferrin saturation (%)

25.00 (16.55, 34.00)

25.70 (17.00, 35.00)

24.00 (15.25, 31.90)

0.45

Left ventricular end-diastolic diameter (mm)

48.00 (44.00, 52.00)

47.00 (43.00, 51.00)

48.00 (45.00, 53.00)

0.07

Left atrium diameter (mm)

34.00 (30.00, 39.00)

34.00 (30.00, 39.00)

35.00 (30.00, 39.75)

0.51

Right ventricular diameter (mm)

21.00 (19.00, 23.00)

21.00 (19.00, 23.00)

21.00 (19.00, 23.00)

0.99

Interventricular septum thickness (mm)

10.00 (10.00, 12.00)

10.00 (9.00, 12.00)

11.00 (10.00, 12.00)

0.13

Left ventricular posterior wall thickness (mm)

10.00 (9.00, 11.00)

10.00 (9.00, 11.00)

10.00 (9.00, 11.00)

0.44

Left ventricular ejection fraction (%)

62.00 (60.00, 65.00)

62.00 (60.00, 65.00)

61.00 (58.00, 64.75)

0.14

Left ventricular hypertrophy n (%)

178 (56.0)

114 (54.8)

64 (58.2)

0.65

Cardiac valve calcification n (%)

45 (14.2)

26 (12.5)

19 (17.3)

0.32

24-hour ultrafiltration volume (mL)

334.12 ± 439.66

335.15 ± 421.80

332.17 ± 473.59

0.95

24-hour urine volume (mL)

800.00 (500.00, 1300.00)

900.00 (500.00, 1300.00)

800.00 (500.00, 1237.50)

0.27

Dialysate/plasma creatinine ratio at 4 h

0.58 (0.49, 0.69)

0.57 (0.48, 0.68)

0.60 (0.51, 0.69)

0.10

Follow-up time (months)

31.00 (16.25, 56.00)

35.00 (19.00, 59.75)

25.00 (11.00, 48.00)

 < 0.01

  1. CVE: cardiovascular event. Continuous variables are presented as mean ± standard deviation (for normally distributed data) or median (interquartile range) (for non-normally distributed data). Categorical variables are presented as frequency (percentage). Bold font means P < 0.05