Fig. 3

Analysis of laboratory test variables associated with severe PE. A. A Volcano plot illustrates the 18 laboratory test variables that show significant expression difference between severe PE and healthy controls, with red, blue, grey representing significantly up-regulated, down-regulated, not significantly differentially expressed test variables respectively. The dashed line indicates a significance level of P < 0.05. Ns: not significant. B–O. The comparison of concentration differences of 14 laboratory test variables between severe PE and healthy controls in the cohort I and II datasets. P. A barplot compares the distribution differences of UPRO positivity for severe PE patients and healthy controls