Skip to main content

Table 1 Baseline characteristics of patients in training, validation and test groups

From: Automated machine learning for early prediction of systemic inflammatory response syndrome in acute pancreatitis

Variables

Group

The developing, dataset (n = 1012)

p-value

The test dataset (n = 212)

p-value

Non-SIRS(n = 670)

SIRS(n = 342)

Non-SIRS(n = 165)

SIRS(n = 47)

Sex (%)

Male

374 (55.8)

220 (64.3)

0.011

107 (64.8)

35 (74.5)

0.289

 

Female

296 (44.2)

122 (35.7)

 

58 (35.2)

12 (25.5)

 

Age(mean [IQR])

 

53.50 [40.00, 67.00]

46.50 [34.00, 60.75]

< 0.001

49.00 [37.00, 65.00]

39.00 [33.50, 65.50]

0.138

Etiology (%)

Biliary

308 (46.0)

136 (39.8)

< 0.001

78 (47.3)

15 (31.9)

0.003

 

Hyperlipidemia

101 (15.1)

101 (29.5)

 

23 (13.9)

18 (38.3)

 
 

Alcoholic

32 (4.8)

21 (6.1)

 

18 (10.9)

3 (6.4)

 
 

Others

229 (34.2)

84 (24.6)

 

46 (27.9)

11 (23.4)

 

Smoke (%)

No

591 (88.2)

284 (83.0)

0.05

135 (81.8)

35 (74.5)

0.364

 

Yes

79 (11.6)

58 (17.0)

 

30 (18.2)

12 (25.5)

 

Hypertension (%)

No

447 (66.7)

221 (64.6)

0.551

122 (73.9)

32 (68.1)

0.543

 

Yes

223 (33.3)

121 (35.4)

 

43 (26.1)

15 (31.9)

 

Diabetes (%)

No

580 (86.6)

295 (86.3)

0.969

144 (87.3)

34 (72.3)

0.025

 

Yes

90 (13.4)

47 (13.7)

 

21 (12.7)

13 (27.7)

 

SBP (median [IQR])

 

131.00 [120.00, 143.00]

134.00 [121.00, 144.75]

0.197

130.00 [117.00, 140.00]

128.00 [122.00, 136.50]

0.892

DBP (median [IQR])

 

79.00 [71.00, 85.00]

80.00 [72.00, 88.00]

0.012

75.00 [70.00, 87.00]

80.00 [70.00, 89.00]

0.106

MAP (median [IQR])

 

96.67 [89.33, 104.33]

98.33 [89.75, 106.67]

0.051

92.67 [86.00, 102.67]

96.00 [88.00, 102.83]

0.233

PLT (*109/L) (median [IQR])

 

190.00 [152.25, 234.00]

204.00 [162.00, 247.50]

0.005

210.00 [170.00, 248.00]

217.00 [173.00, 270.00]

0.262

WBC (*109/L) (median [IQR])

 

10.73 [8.26, 13.80]

15.40 [12.74, 18.84]

< 0.001

11.10 [8.40, 13.40]

15.60 [12.55, 18.35]

< 0.001

N (*109/L) (median [IQR])

 

8.79 [6.20, 11.67]

13.37 [10.77, 16.58]

< 0.001

9.00 [6.40, 11.60]

13.30 [11.05, 15.90]

< 0.001

L (*109/L) (median [IQR])

 

1.27 [0.80, 1.90]

1.10 [0.70, 1.60]

0.001

1.30 [0.80, 1.80]

1.00 [0.60, 1.65]

0.041

HCT (L/L) (median [IQR])

 

0.42 [0.39, 0.46]

0.44 [0.40, 0.47]

< 0.001

0.43 [0.40, 0.48]

0.44 [0.41, 0.48]

0.267

RDW (%) (median [IQR])

 

12.80 [12.40, 13.40]

12.90 [12.40, 13.40]

0.843

12.80 [12.40, 13.30]

12.80 [12.30, 13.05]

0.644

Lr (%) (median [IQR])

 

12.35 [7.20, 18.67]

6.90 [4.40, 10.97]

< 0.001

12.60 [8.10, 17.80]

6.90 [3.90, 11.45]

< 0.001

Cr (µmol/L) (median [IQR])

 

64.00 [54.52, 76.25]

62.00 [49.10, 75.57]

0.011

65.00 [55.00, 75.00]

65.00 [51.50, 75.50]

0.741

TB (µmol/L) (median [IQR])

 

20.70 [14.53, 32.10]

22.45 [15.33, 32.12]

0.335

17.40 [12.10, 27.30]

17.30 [12.65, 23.80]

0.673

DB (µmol/L) (median [IQR])

 

7.10 [4.60, 13.80]

7.60 [4.12, 12.80]

0.642

8.00 [5.50, 13.50]

8.30 [5.05, 12.25]

0.583

Urea (mmol/L) (median [IQR])

 

4.80 [3.80, 6.20]

5.20 [3.90, 7.00]

0.005

4.20 [3.40, 5.80]

4.30 [3.55, 7.25]

0.159

LDH (U/L) (median [IQR])

 

211.00 [171.93, 287.00]

260.80 [209.72, 390.75]

< 0.001

193.00 [163.00, 236.00]

271.00 [174.00, 351.00]

< 0.001

Ca2+(mmol/L) (median [IQR])

 

2.18 [2.08, 2.29]

2.08 [1.95, 2.23]

< 0.001

2.11 [2.01, 2.21]

2.06 [1.92, 2.16]

0.035

TG (mmol/L) (median [IQR])

 

1.31 [0.84, 2.52]

1.94 [1.08, 5.93]

< 0.001

1.01 [0.64, 2.31]

2.28 [0.95, 8.34]

0.001

GLU (mmol/L) (median [IQR])

 

6.95 [5.70, 8.92]

7.72 [6.23, 10.38]

< 0.001

6.64 [5.43, 8.82]

10.46 [7.14, 13.70]

< 0.001

ALT (U/L) (median [IQR])

 

41.90 [19.00, 144.50]

30.30 [16.83, 78.07]

0.001

43.00 [19.00, 162.00]

21.00 [13.00, 66.00]

0.018

AST (U/L) (median [IQR])

 

33.20 [19.18, 100.50]

26.90 [17.22, 53.73]

< 0.001

29.00 [17.00, 77.00]

23.00 [16.00, 48.50]

0.088

GGT (U/L) (median [IQR])

 

89.55 [33.62, 281.55]

78.20 [38.23, 203.95]

0.437

102.00 [40.00, 273.00]

103.00 [42.50, 197.00]

0.824

ALP (U/L) (median [IQR])

 

92.10 [69.90, 141.75]

78.00 [59.50, 106.90]

< 0.001

85.00 [67.00, 135.00]

83.00 [64.00, 104.50]

0.325

ALB (g/L) (median [IQR])

 

37.20 [33.90, 40.60]

35.00 [31.80, 39.00]

< 0.001

38.90 [35.40, 41.10]

36.60 [33.45, 39.50]

0.005

K+(U/L) (median [IQR])

 

3.99 [3.72, 4.30]

3.98 [3.73, 4.28]

0.772

4.11 [3.84, 4.39]

4.24 [4.00, 4.51]

0.066

PT (s) (median [IQR])

 

13.00 [12.20, 14.00]

13.50 [12.50, 14.70]

< 0.001

13.70 [13.20, 14.50]

14.00 [13.40, 14.75]

0.173

INR (median [IQR])

 

1.07 [1.01, 1.15]

1.11 [1.02, 1.22]

< 0.001

1.06 [1.02, 1.14]

1.10 [1.02, 1.16]

0.212

APTT (s) (median [IQR])

 

31.40 [28.20, 35.70]

33.20 [28.72, 38.00]

0.002

37.00 [34.20, 41.30]

37.30 [34.15, 41.10]

0.97

CRP (mg/L) (median [IQR])

 

13.62 [2.50, 75.72]

109.72 [16.58, 208.45]

< 0.001

66.50 [15.10, 127.10]

165.30 [113.95, 238.45]

< 0.001

  1. SBP, Systolic blood pressure; DBP, Diastolic blood pressure; MAP, Mean artery pressure; N, Neutrophil count; L, Lymphocyte count; Lr, Percentage of lymphocytes; Cr, Creatinine; TB, Total bilirubin; DB, Direct bilirubin; TG, Total triglycerides; GLU, Glucose; ALB, Albumin
Back to article page

BMC Medical Informatics and Decision Making

ISSN: 1472-6947

Contact us