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Table 4 Comparison of different approaches in terms of key factors

From: MISTIC: a novel approach for metastasis classification in Italian electronic health records using transformers

Criterion

Zero-shot BERT

Generative LLM

Rule-based

MISTIC

Training data

No

No

Predefined rules

Few

Explainability

No

No

Yes

Yes

Generalization

Yes

Yes

No

Yes

Computational demand

Moderate

High

Low

Moderate

Automation

Full

Full

Partial

Full

Manual effort

Low

Low

High

Low