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Table 1 Clinical characteristics of patients with mild, moderate and severe HAPE

From: A machine learning-based severity stratification tool for high altitude pulmonary edema

Characteristic

Mild, N = 671

Moderate, N = 2401

Severe, N = 291

p-value2

Sex

   

0.3

 Female

18(27%)

45(19%)

7(24%)

 

 Male

49(73%)

195(81%)

22(76%)

 

Age

35 (27, 42)

31 (26, 42)

40 (27, 44)

0.089

Height

169 (165, 172)

170 (165, 173)

169 (163, 171)

0.3

Weight

74 (64, 77)

74 (64, 77)

75 (69, 78)

0.5

BMI

24.9 (22.9, 26.3)

24.8 (23.0, 26.4)

25.5 (23.8, 26.4)

0.6

Fatigue

15 (22%)

60 (25%)

7 (24%)

> 0.9

Loss of taste

15 (22%)

56 (23%)

6 (21%)

> 0.9

Nausea

12 (18%)

46 (19%)

12 (41%)

0.017

Sleep disorder

17 (25%)

47 (20%)

8 (28%)

0.4

Dizzy

37 (55%)

155 (65%)

21 (72%)

0.2

Cough

57 (85%)

205 (85%)

25 (86%)

> 0.9

Short breath

34 (51%)

125 (52%)

16 (55%)

> 0.9

Dyspepsia

17 (25%)

54 (23%)

7 (24%)

0.9

Palpitations

12 (18%)

46 (19%)

4 (14%)

0.8

Bluish lips

11 (16%)

36 (15%)

2 (6.9%)

0.5

Sputum

   

> 0.9

 No

62 (93%)

219 (91%)

27 (93%)

 

 Yes

5 (7.5%)

20 (8.3%)

2 (6.9%)

 

Lung reals

   

2.2E-16

 None

11 (16%)

55 (23%)

2 (6.9%)

 

 Unilateral or bilateral lung floor rales (small amount)

41 (61%)

124 (52%)

3 (10%)

 

 Unilateral or bilateral middle and lower lobes of the lungs (moderate amount)

15 (22%)

60 (25%)

2 (6.9%)

 

 Large amount of rales (full lungs)

0 (0%)

1 (0.4%)

22 (76%)

 

Temperature

36.50 (36.30, 36.70)

36.50 (36.40, 36.80)

36.50 (36.50, 36.80)

0.4

Heart rate

90 (80, 100)

100 (87, 119)

100 (92, 115)

< 0.001

SpO2

80 (74, 86)

74 (65, 84)

74 (63, 85)

0.007

SBP

122 (117, 133)

120 (111, 130)

120 (117, 130)

0.3

DBP

80 (74, 88)

80 (70, 87)

77 (70, 83)

0.6

CT

   

< 0.001

 Normal

7 (10%)

2 (0.8%)

0 (0%)

 

 Double lung/texture

10 (15%)

8 (3.3%)

2 (6.9%)

 

 Bipulmonary lower field inner bands/patchy/bipulmonary lower field inner bands/flocculent

50 (75%)

21 (8.8%)

7 (24%)

 

 Others

0 (0%)

209 (87%)

20 (69%)

 
  1. 1Median (IQR); n (%) 2 Kruskal-Wallis rank sum test; 2 Pearson’s Chi-squared test; Fisher’s exact test