Table 1 Baseline characteristics of study participants

Age, median (IQR)—years

69(19)

66(18)

74(11)

< 0.001

Sex—%. (no)

0.060

 Male

66.57(239)

70.71(169)

60.83(73)

 Female

33.43(120)

29.29(70)

39.17(47)

SBP, mean (SD)—mmHg

158.58(25.42)

158.48(26.72)

158.8(22.60)

0.399

DBP, median (IQR)—mmHg

89(19)

88(18)

90(20)

0.679

Medical history

Atrial Fibrillation—%. (no)

18.66(67)

14.05(34)

28.21(22)

0.001

Hypertension—%. (no)

67.96(244)

63.64(154)

76.92(90)

0.011

Diabetes mellitus—%. (no)

18.38(66)

15.29(37)

24.79(29)

0.029

Smoking—%. (no)

13.65(49)

12.40(30)

16.24(19)

0.320

Transient ischemic attack/ Cerebral infarction—%. (no)

15.88(57)

17.77(43)

11.97(14)

0.159

Biochemical variables

WBC, median (IQR)—109/L

7.68(3.56)

7.19(3.05)

8.92(4.11)

< 0.001

Cr, median (IQR)—umol/L

66(22.0)

65(20)

70(32)

0.049

Glu, median (IQR)—mmol/L

6.95(2.88)

6.77(2.65)

7.38(3.40)

0.024

TG, median (IQR)—mmol/L

1.13(0.69)

1.19(0.73)

1.05(0.61)

0.148

TC, mean (SD)—mmol/L

4.44(1.04)

4.38(1.29)

4.55(1.10)

0.307

HDL-C, median (IQR)—mmol/L

1.00(0.3)

1.00(0.3)

1.1(0.4)

0.137

LDL-C, mean (SD)—mmol/L

2.79(0.93)

2.74(0.92)

2.89 (0.95)

0.221

ALB, mean (SD)-g/L

38.96(3.92)

39.32(3.70)

38.22(4.27)

0.013

LDH, median (IQR)—U/L

182.30(60.6)

174.6(43.8)

211.8(73.9)

< 0.001

LAR, median (IQR)

4.71(1.65)

4.46(1.39)

5.54(1.91)

< 0.001

NIHSS—%. (no)

< 0.001

 Excellent (0–4)

42.90(154)

54.55(132)

18.80(22)

 Poor (5–42)

57.10(205)

45.45(110)

81.20(95)

Treatment decisions—%. (no)

0.066

 IV rt-PA

91.92(330)

90.08(218)

95.73(112)

 IV rt-PA + EVT

8.08(29)

9.92 (24)

4.27(5)

TOAST—%. (no)

< 0.001

 LAA

56.27(202)

52.48(127)

64.10(75)

 CE

20.06(72)

54.17(39)

28.21(33)

 Other

23.68(85)

31.40(76)

7.69(9)