Table 1 Basic anthropometric, biochemical and immunological characteristics of 80 control people and 80 T2DM patients. The student t-test was applied to data that presented as mean ± standard deviations (SD)
variables | Non-T2DM | T2DM | P-value | ||
|---|---|---|---|---|---|
Mean ± SD | Mean ± SD | ||||
Age (Year) | 55.71 | 7.06 | 57.48 | 7.85 | 0.13 |
BMI (kg/m2) | 25.73 | 3.87 | 25.91 | 4.08 | 0.77 |
SBP (mmHg) | 128.56 | 15.90 | 129.40 | 17.49 | 0.75 |
DBP (mmHg) | 79.80 | 13.42 | 80.85 | 13.10 | 0.62 |
FBG (mg/dl) | 90.91 | 10.95 | 155.41 | 22.92 | < 0.001 |
Insulin (µU/ml) | 4.77 | 3.13 | 10.52 | 4.77 | < 0.001 |
Adiponectin (µg/ml) | 13.56 | 3.52 | 9.12 | 2.74 | < 0.001 |
TNF-alpha (pg/ml) | 19.34 | 7.14 | 28.69 | 7.62 | < 0.001 |
IL-6 (pg/ml) | 4.76 | 1.95 | 9.78 | 3.32 | < 0.001 |
HOMA-IR | 1.08 | 0.72 | 4.11 | 2.13 | < 0.001 |
Creatinine (mg/dl) | 1.13 | 0.16 | 1.14 | 0.12 | 0.51 |
AST (U/l) | 18.47 | 5.66 | 17.63 | 5.54 | 0.34 |
ALT (U/l) | 19.18 | 8.41 | 18.14 | 7.39 | 0.40 |
TG (mg/dl) | 125.30 | 50.18 | 162.10 | 54.83 | < 0.001 |
TC (mg/dl) | 169.42 | 45.93 | 191.49 | 42.91 | 0.002 |
LDL-C (mg/dl) | 101.14 | 33.20 | 117.66 | 34.03 | 0.002 |
HDL-C (mg/dl) | 45.28 | 8.17 | 42.12 | 5.50 | 0.005 |
CCN6 (pg/ml) | 1979.17 | 471.99 | 1259.76 | 395.02 | < 0.001 |