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Table 1 Statistical analysis of baseline indicators and clinical characteristics of patients with benign and malignant ovarian tumors

From: Decision tree model for predicting ovarian tumor malignancy based on clinical markers and preoperative circulating blood cells

Variable

Total

Malignant tumor (n = 224)

Benign tumor (n = 534)

P-value

Normal information

Age

41.97 ± 16.16

50.50 ± 14.09

38.39 ± 15.64

< 0.001

BMI

22.46 ± 2.45

22.60 ± 2.47

22.40 ± 2.44

0.257

Course of disease (days)

307.72 ± 740.25

149.49 ± 464.49

374.09 ± 820.40

< 0.001

General condition

   

< 0.001

good( 1 )

41(5.41%)

5(2.23%)

36(6.74%)

 

medium( 2 )

713(94.06%)

215(95.98%)

498(93.26%)

 

cachexia ( 3 )

4(0.53%)

4(1.79%)

-

 

Imaging indicators

Mass size (BUS)

85.58 ± 51.97

103.10 ± 46.04

78.24 ± 52.59

< 0.001

Mass size (MR/CT)

89.25 ± 65.57

105.67 ± 62.45

82.36 ± 65.68

< 0.001

Mass locations (BUS)

   

0.284

Unilateral ( 1 )

682(89.97%)

197(87.95%)

485(90.82%)

 

Bilateral ( 2 )

76(10.03%)

27(12.05%)

49(9.18%)

 

Mass locations (MR/CT)

   

1

Unilateral ( 1 )

647(85.36%)

191(85.27% )

456(85.39%)

 

Bilateral ( 2 )

111(14.64%)

33(14.73%)

78(14.61%)

 

Post-menopause

   

< 0.001

No ( 1 )

461(60.82%)

79(35.27%)

382(71.54%)

 

Yes ( 2 )

297(39.18%)

145(64.73%)

152(28.46%)

 

Ascites (palpation)

   

< 0.001

Yes ( 1 )

39(5.15%)

33(14.73%)

6(1.12%)

 

No ( 2 )

719(94.85%)

191(85.27%)

528(98.88%)

 

Tumor markers

    

HE4 (pmol/L)

212.10 ± 537.10

515.23 ± 893.93

84.95 ± 143.39

< 0.001

CA125 (U/mL)

332.66 ± 1120.92

971.25 ± 1911.41

64.79 ± 112.53

< 0.001

ROMA_before

25.52 ± 28.60

53.86 ± 36.55

13.64 ± 11.13

< 0.001

ROMA_after

30.65 ± 28.30

60.85 ± 33.65

17.98 ± 10.92

< 0.001

Red blood cell related indicators

RBC

4.18 ± 0.43

4.06 ± 0.47

4.24 ± 0.40

< 0.001

HGB

121.82 ± 14.68

116.47 ± 15.76

124.07 ± 13.60

< 0.001

HCT

37.51 ± 3.98

36.19 ± 4.42

38.06 ± 3.65

< 0.001

RDW

13.12 ± 1.62

13.37 ± 1.97

13.01 ± 1.44

< 0.001

MCV

89.88 ± 6.85

89.39 ± 6.68

90.08 ± 6.91

0.016

MCH

29.18 ± 2.76

28.75 ± 2.60

29.36 ± 2.80

< 0.001

MCHC

324.28 ± 12.12

321.37 ± 11.23

325.50 ± 12.28

< 0.001

White blood cell related indicators

WBC

6.45 ± 2.17

7.03 ± 2.67

6.20 ± 1.87

< 0.001

NE%

60.69 ± 11.26

67.76 ± 11.00

57.73 ± 9.98

< 0.001

NE

4.04 ± 2.06

4.95 ± 2.55

3.66 ± 1.68

< 0.001

MO%

6.50 ± 1.94

6.82 ± 2.07

6.37 ± 1.86

0.006

MO

0.41 ± 0.16

0.46 ± 0.19

0.38 ± 0.13

< 0.001

BA%

0.43 ± 0.24

0.40 ± 0.23

0.44 ± 0.24

0.051

BA

0.03 ± 0.01

0.03 ± 0.02

0.03 ± 0.01

0.994

EO%

2.20 ± 1.89

1.91 ± 2.00

2.32 ± 1.84

< 0.001

EO

0.13 ± 0.12

0.12 ± 0.12

0.14 ± 0.12

0.005

LY

1.83 ± 0.65

1.46 ± 0.55

1.99 ± 0.63

< 0.001

LY%

30.10 ± 10.22

23.01 ± 9.94

33.08 ± 8.78

< 0.001

Platelet related indicators

PLT

247.02 ± 83.61

288.03 ± 112.71

229.82 ± 60.08

< 0.001

MPV

10.51 ± 1.35

10.22 ± 1.35

10.64 ± 1.34

< 0.001