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Table 3 Characteristics of the studies included in the systematic review

From: Artificial intelligence-based risk assessment tools for sexual, reproductive and mental health: a systematic review

Author

Study Design

Purpose

population

Comparator

Outcome

Solution category

Huang et al 2023 [23]

Retrospective cross-sectional study

Identify major risk factors affecting male sperm count using machine learning predictive models

Male individuals underwent annual health screening

Traditional multiple linear regression

Identified major risk factors affecting male sperm count

Prediction tool

Chen et al 2023 [24]

observational and retrospective.

Develop and evaluate machine learning models for the prediction of cervical cancer

Patients at risk of cervical cancer

Comparison with other machine learning models

performance metrics evaluation for predicting cervical cancer in patients at risk

Prediction tool

Hariprasad et al 2023 [25]

retrospective observational study

Develop an efficient risk prediction model for cervical cancer using machine learning techniques

Female patients

Comparison with existing models

Improved performance metrics in predicting cervical cancer risk

Prediction tool

Al Ghadban et al 2023 [26]

Prospective case-cohort study

Utilize machine learning models on metabolic data to predict spontaneous preterm birth in pregnant women

Pregnant women at risk of spontaneous preterm birth

Standard clinical assessment

Accuracy of predicting spontaneous preterm birth

Prediction tool

Shivangi et al 2023 [27]

observational and analytical

Predict and analyze Polycystic Ovary Syndrome using machine learning techniques

Women with polycystic ovary syndrome

Traditional diagnostic methods

Identification of important indicators

Prediction tool

Allen et al 2023 [28]

Observational study

Utilize natural language processing techniques to indirectly identify psychosocial risks

Pregnant and postpartum women

N/A

Identify psychosocial risks during the perinatal period through the analysis of language patterns

Screening tool

Chen et al 2023 [29]

Retrospective, observational study

Develop and evaluate a machine learning-based prediction model for prostate cancer

Patients with suspected prostate cancer

Comparison with classical PSA predictors

Improved accuracy in predicting prostate cancer diagnosis

Prediction tool

Cersonsky et al 2023 [30]

Observational study

Create and refine machine learning models for predicting stillbirth

Pregnant women

Previous predictive models using logistic regression

Accuracy and sensitivity in predicting stillbirth

Prediction tool

Shen et al 2023 [31]

modelling cost-effectiveness analysis

Assess the cost-effectiveness of AI-assisted liquid-based cytology testing for cervical cancer screening

Women in China

Traditional screening methods

Cost-effectiveness for cervical cancer screening

Screening tool

Reátegui et al 2022 [32]

Observational and comparative study

Identify patterns in sociodemographic and clinical information related to cervical cancer in women with HPV

Women with an active sexual life

Different cytology results, age groups, and marital statuses

Identification of patterns related to cervical cancer

Assessment tool

Xu et al 2022 [33]

Prospective

Develop a web-based risk prediction tool for HIV and STIs using machine learning algorithms

Individuals seeking HIV and STI risk assessment

Traditional risk assessment

Personalized risk assessment for HIV and STIs

prediction tool

Li et al 2022 [34]

Retrospective cohort study

Develop and validate an algorithm for predicting the risk of preeclampsia in pregnant women

Pregnant women

N/A

Improved prediction accuracy and identification of risk factors for preeclampsia

prediction tool

Amitai et al 2023 [35]

Cross-Sectional Study

To predict the risk of first-trimester miscarriage in cleavage-stage embryos during IVF

Women Cleavage-stage embryos

Traditional assessment methods

Prediction of first-trimester miscarriage

prediction tool

Blass et al 2022 [36]

Retrospective cohort

Endometriosis prediction using machine learning algorithms

Women with endometriosis

N/A

Prediction model performance

prediction tool

Pawar et al 2022 [37]

Cross-sectional

Develop a robust machine learning predictive model for maternal health risk assessment

Pregnant women

Traditional machine learning algorithms

Maternal health risk prediction

prediction tool

Xu et al 2022 [38]

Retrospective study

Develop and validate a machine-learning-based risk prediction tool for HIV and three common STIs acquisition over the next 12 months

Individuals at risk of HIV and STI acquisition

N/A

Prediction of HIV and STI acquisition

prediction tool

Jun et al 2022 [39]

Retrospective observational study

Identify the risk factors of cervical cancer in women

Women in a private hospital

Women without cervical cancer

Identification of risk factors for cervical cancer

prediction tool

Bendifallah et al 2022 [40]

Retrospective cross-sectional study

Investigate the potential of machine learning algorithms as a screening approach for patients with endometriosis

Women with endometriosis

Traditional diagnostic methods

Accuracy of endometriosis diagnosis

Screening tool

Nsugbe et al 2022 [41]

Retrospective study

To develop a predictive model for the early detection using machine learning

Women with endometrial cancer or atypical hyperplasia

Standard diagnostic methods

Early and accurate diagnosis of endometrial cancer

Diagnosis tool

Sanderson et al 2020 [42]

Case-control study design

Predicting the risk of death by suicide following an emergency department visit for parasuicide

Individuals visited the emergency department for parasuicide

N/A

Quantification of suicide risk in a clinical setting

Prediction tool

Bao et al 2021 [43]

Retrospective study

Predict the diagnosis of HIV and sexually transmitted infections among men who have sex with men

Men who have sex with men

N/A

Diagnosis of HIV and sexually transmitted infections

Prediction tool

Metsker et al 2020 [44]

Retrospective, observational, data-driven

To develop a data-driven model using machine learning methods for the prediction of a labor due date based on pregnancy history

Female patient with underwent treatment

N/A

Prediction of a labor due date to allow proper resource planning

Prediction tool

Petrozziello et al 2019 [45]

Observational, retrospective cohort study

To develop and evaluate the performance of MCNN for fetal compromise detection

Pregnant women in labor

Traditional visual examination of CTG

Improved accuracy in detecting fetal compromise during labor and delivery

Diagnosis tool

Silva et al 2019 [46]

Experimental

To develop and evaluate the performance of LSTM networks for predicting cervical cancer

Women with suspected cervical cancer

performance comparison of different metaheuristic optimizers

Improved accuracy in cancer diagnosis

Prediction tool

King et al 2018 [47]

Retrospective observational study

To develop and validate triage algorithms to predict STI diagnoses

MSM and young people

N/A

Identification of factors associated with new STI diagnoses

Prediction tool

Bruno et al 2023 [48]

Cross-sectional Cohort study

Explore the potential of machine learning to predict changes in depressive symptoms

Patients with subclinical depression

Symptom changes over time

Forecasting of symptom changes using machine learning

Prediction tool

Foltz et al 2022 [49]

Cross-Sectional Study

Reflect on the nature of measurement in language-based automated assessments of patients’ mental state and cognitive function

Patients undergoing automated assessment

Traditional assessment methods

Improved measurement accuracy and efficiency

Prediction tool

Adeli et al 2023 [50]

Longitudinal study

Dynamically estimate the short-term risk of falls (within the next 4 weeks) using ambient gait monitoring and clinical data

Older adults with dementia

N/A

Estimation of fall risk within the next 4 weeks

Prediction tool

Msosa et al 2023 [51]

Retrospective observational

Develop predictive models for mental health crisis prediction among individuals with depression

Mental health service users

N/A

Development and evaluation of predictive models for mental health crisis prediction

Assessment tool

Ilias et al 2023 [52]

Experimental study

Propose and evaluate a solution for identifying stress and depression in social media using transformer-based models

Social media users

Performance of transformer-based models

Improved model performance to identify differences between stressful and nonstressful texts

Screening tool

Biplob et al 2023 [53]

Predictive study

Use machine learning algorithms to predict suicidal ratios across different continents

Individuals at risk of suicide

Different machine learning algorithms performance

Prediction of suicidal ratio

Prediction tool

Popat et al 2023 [54]

Computational and clinical research study

To explore the use of uncertainty-aware deep learning models for diagnosing mental health conditions using clinical patient health record data

Patients with mental health conditions

Traditional decision-making approaches meaning health care professionals

Improved clinical decision-making

Support tool

Akhlaghi et al 2023 [55]

Prospective observational study

Demonstrate deep Learning models to support clinical decision-making

Patients with mental health conditions

Traditional machine learning models and clinical diagnostic methods

Improved accuracy and reliability of clinical decision-making

Support tool

Berge et al 2023 [56]

Qualitative co-design workshop

Design and evaluate AI-enhanced decision support during telephone triage

Mental health patient

Traditional telephone triage workflow

Improved clinical assessment and documentation

Support tool

Lu et al 2022 [57]

Retrospective cohort study

Develop and evaluate ML models for the prediction of suicidal events

Inmates in a correctional setting

Comparison of the performance of AI algorithms

Improved prediction of suicidal and self-injurious events and enhanced sensitivity and specificity

Prediction tool

Miles et al 2022 [58]

Cohort study

Develop and validate a risk prediction model to support ambulance clinical transport decisions

Conveyed ambulance patients

Standard transport decision-making

Avoidable ED attendances

Prediction tool

Aulia et al 2022 [59]

Experimental study

Develop a machine learning solution for predicting depression

Indonesian Twitter users

Different data scenarios and pre-trained language models

Developed machine learning approaches for predicting depression

Prediction tool

Skaik et al 2022 [60]

Computational research study

Develop and evaluate a predictive model for depression by filling out the Beck’s Depression Inventory questionnaire

Social media users in Canada

N/A

Predicted depression levels

Prediction tool

Monreale et al 2022 [61]

Observational and analytical

Identify mental-health related patient from subreddits

Reddit users with addiction, anxiety, and depression

Performance of different models and subsets of LIWC features

Detection and classification accuracy

Prediction tool

Shea et al 2022 [62]

Observational cohort study

Identify autistic adults enrolled in Medicaid programs

Autistic adults not enrolled in Medicaid

Gold standard clinical assessment

Developed and evaluated a PRE tool to identify Medicaid-enrolled autistic adults

Diagnosis tool

Sun et al 2022 [63]

Mixed study

Improving user control for explainable online symptom checkers

Users of online symptom checkers

Static disclosure of all explanations

Perceived transparency and affective trust

Support tool

McCosker et al 2023 [64]

Qualitative case study

Propose an integrated approach to managing the interaction between human and machine moderators

Mental health patient

Traditional moderation practices

Improved mental health services

Support tool

Rozova et al 2022 [65]

Retrospective analysis

Develop an automated system for detecting self-harm presentations in ED triage notes using NLP

Emergency Department (ED) patients

Traditional machine learning and deep learning Model

Accurate identification of self-harm presentations

Diagnosis tool

Martinez-Eguiluz et al 2023 [66]

Predictive study

To evaluate machine learning algorithms for the classification of Parkinson’s disease

Patients with Parkinson’s disease

Comparison of performance of machine learning algorithms

Prediction of Parkinson’s disease based on non-motor clinical features

Prediction tool

Xu et al 2021 [67]

Secondary anonymous data analysis

suicide detection in online counseling systems

Users aged 11–35

With BiLSTM deep learning model

Identified crisis cases and provided real-time feedback to counselors

Diagnosis tool

Dharma et al 2021 [68]

Computational analysis

Develop a model for predicting mental health disorders among tech workers

Tech workers

Performance of SVM and FCNN algorithms in predicting mental health disorders

Accuracy rate of the algorithms in predicting mental health disorders

Diagnosis tool

Annapureddy et al 2021 [69]

Retrospective observational study

Develop a personalized decision support system to predict the risk of persistent PTSD severity in veterans

Combat veterans suffering from PTSD

Standard care or other predictive models

Improved prediction and prevention of long-term crisis in veterans with PTSD

Assessment tool

Ameratunga et al 2022 [70]

Cross-sectional

To investigate the prevalence and predictors of post-traumatic stress symptoms in injured

Injured New Zealanders

Hospitalised vs. non-hospitalised participants

Prevalence and predictors of post-traumatic stress symptoms

Prediction tool

Simpson et al 2021 [71]

Retrospective cohort study

Evaluate the performance of the (C-SSRS) Screener in predicting suicide risk and self-harm after ED discharge

Adult patients in the emergency department (ED)

N/A

Prediction of suicide risk and ED visits for self-harm

Prediction tool

van der Schyff et al 2023 [72]

Interventional Study

To explore the potential of AI-based chatbots to provide mental health support

Mental health chatbot user

Traditional mental health support

Effectiveness and accessibility

Support tool

Haines-Delmont et al 2020 [73]

Retrospective analysis

Explore the feasibility of using digital phenotyping and machine learning to predict suicide risk using phone measurements

Patients in acute mental health

N/A

Prediction of suicide risk using data collected from the SWiM app

Prediction tool

Lin et al 2020 [74]

Historical cohort study

To utilize machine learning techniques to predict the presence of suicide ideation in military personnel

Military men and women aged 18–50 years

N/A

Prediction of suicide ideation in military personnel based on psychological stress domains

Prediction tool

Baek et al 2020 [75]

Predictive modeling study

Accurately predict the risk of depression based on various contextual factors

Individuals at risk of depression

Traditional regression analysis

Accurate prediction of depression risk based on various factors

Prediction tool

Howard et al 2020 [76]

Predictive modeling study

Benchmark multiple methods of text feature representation and compare their downstream

social media users

N/A

Prediction of risk classification for social media posts

Prediction tool

Ferraro et al 2020 [77]

Predictive and data-driven study

To develop and evaluate automated text classification methods for triaging from online group texts

Internet support groups for mental health

Traditional manual moderation

Identification of crisis posts

Screening tool

Chen et al 2020 [78]

Retrospective observational study

To develop and evaluate natural language processing-based models for predicting short-term emergency department

Adult non-trauma outpatients

Reference model without NLP methods

Improvement in performance metrics (MSE or MAE) for predicting short-term emergency department length of stay

Prediction tool

Si et al 2019 [79]

Cross-sectional study

To distinguish between the speech of patients who suffer from mental disorders causing psychosis

Participant with psychosis

Utilization of word embeddings and CNN

Prediction rate in distinguishing between the speech of psychosis patients and healthy individuals

Prediction tool

Wang et al 2019 [80]

Computational linguistic analysis

To develop a reliable and efficient method for identifying depression risk in Chinese microblogs

Users of Chinese microblogs

N/A

Assessment of depression risk based on microblog content

Assessment tool

Shrestha et al 2019 [81]

Observational study

Address the problem of detecting depressed users in online forums

Users of the ReachOut.com online forum

Comparison of linguistic features to evaluate their effectiveness

Detection of depressed users and identification of at-risk individuals for appropriate support and intervention

Prediction tool

McCoy et al 2019 [82]

Retrospective cohort study

To determine the length of stay in ED

Children and adolescents in ED

Comparison of dimensional psychopathology scores

Length of stay and probability of hospital admission

Prediction tool

Yang et al 2020 [83]

Cross-sectional study

To enhance understanding of the underlying psychosocial factors associated with dementia in older adults to improve diagnosis

Older adults aged 50 years

N/A

Identification of potential risk factors for dementia

Prediction tool

Milne et al 2019 [84]

Retrospective

To evaluate the effectiveness of an automated triage system in improving moderator responsiveness in online peer support

Moderators of online peer support forums

Moderator behaviour before the introduction of the triage system

Evaluation of the accuracy of the triage systems

Support tool

Singh et al 2018 [85]

Observational study

To explore the potential of using mobile phone metadata to automatically assess an individual’s mental health

People with mental health problem

Traditional assessment methods

Automated and accurate mental health assessment

Assessment tool