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Table 2 Calculating performance test-characteristics

From: Digital monitoring of medication safety in children: an investigation of ADR signalling techniques in Malaysia

Result/Signal

Gold standard (Listed events)

Total

Positive predictive value (PPV) =

a / (a + b)

Labelled

Not labelled

 

Yes

a (true positive, TP)

b (false positive, FP)

a + b

 

No

c (false negative, FN)

d (true negative, TN)

c + d

Negative predictive value (NPV) = d / (c + d)

Total

a + c

b + d

 

Sensitivity = a/(a + c)

Specificity = d / (b + d)