Fig. 1

Flowchart of the design including somatic mutation visualization and TMB prediction model construction. ESCA, esophageal carcinoma; STAD, stomach adenocarcinoma; COAD, colon adenocarcinoma; READ, rectum adenocarcinoma; TMB, tumor mutation burden; DEGs, differentially expressed genes; Lasso, least absolute shrinkage and selection operator; r, Pearson relevance coefficient; R2, the coefficient of determination