Table 1 The characteristics of the relapsed and non-relapsed PC patients
From: Prediction of 12-month recurrence of pancreatic cancer using machine learning and prognostic factors
Features | Values | Total (n = 566) | Relapsed (n = 268) | Non-relapsed (n = 298) | Skewness | Kurtosis | P-value |
|---|---|---|---|---|---|---|---|
Age (year) | < 45 45–65 > 65 | 107 269 190 | 37 101 130 | 70 168 60 | -0.328 | 1.225 | P = 0.02 |
Gender | Male Female | 279 287 | 129 139 | 150 148 | -0.112 | 1.089 | P = 0.21 |
BMI | <=25 > 25 | 317 249 | 156 112 | 161 137 | 0.326 | 1.127 | P = 0.1 |
Duration of hospital stay | < 1 week 1–2 week > 2 week | 75 120 371 | 22 65 181 | 53 55 190 | -0.594 | 1.484 | P = 0.08 |
Surgery method | Cephalic duodenopancreatectomy Distal pancreatectomy | 378 188 | 197 71 | 181 117 | 0.828 | 1.527 | P = 0.06 |
Chemotherapy | Yes No | 422 144 | 165 103 | 257 41 | 1.124 | 2.183 | P < 0.01 |
Radiotherapy | Yes No | 471 95 | 192 76 | 279 19 | 1.347 | -2.327 | P < 0.01 |
Resectability | Resectable Borderline resectable | 395 171 | 218 50 | 177 121 | 0.835 | 1.288 | P < 0.01 |
Resection margin | Positive Negative | 398 168 | 201 67 | 197 101 | 0.854 | 1.441 | P < 0.01 |
Histological type | Adenocarcinoma, Squamous cell carcinoma, Other types | 401 143 22 | 192 59 17 | 209 84 5 | 0.891 | -1.225 | P = 0.08 |
Tumor grade | Grade 1 (Well differentiated), Grade 2 (Moderately differentiated), Grade 3 (Poorly differentiated), Grade 4 (Undifferentiated) | 85 245 173 63 | 51 131 58 28 | 34 114 115 35 | 0.216 | 1.106 | P = 0.02 |
T-stage (Tumor size) | T1 T2 T3 T4 | 67 176 185 138 | 17 58 111 82 | 50 118 74 56 | -0.356 | 1.725 | P = 0.03 |
N-stage (Lymph node invasion) | N0 N1 N2 | 118 211 237 | 48 84 136 | 70 127 101 | -0.324 | 1.583 | P < 0.01 |
M-stage (Metastasis state) | M0 M1 | 125 441 | 43 225 | 82 516 | -1.081 | 0.897 | P < 0.01 |
mGPS | 0 1 2 | 68 228 270 | 26 101 141 | 42 127 129 | -0.807 | 1.113 | P < 0.01 |
lymph node metastasis | Yes No | 401 165 | 215 53 | 186 112 | 0.989 | 1.082 | P < 0.01 |
Vascular resection | No Venous Arterial | 97 217 252 | 33 102 133 | 64 115 119 | -0.623 | -1.126 | P = 0.04 |
Peritoneal cytology | Positive Negative | 398 168 | 188 80 | 210 88 | 0.917 | 0.495 | P = 0.08 |