Figure 1
From: Improved method for protein complex detection using bottleneck proteins
Example PPI network and bottleneck information. First, Betweenness centrality of each node in the PPI network is calculated. Protein nodes are sorted according to the betweenness centrality in descending order, and put into starting node set. All nodes keep close bottlenecks, which means distance between node and bottleneck ≤ 2.